Police were called to Kilmington Drive, Cheetham Hill, shortly before 5.45pm on Wednesday 12 November 2008, following reports of concern for welfare.
Officers attended and found the bodies of a three-month-old baby and a three-year-old child A 21-year-old woman has been arrested on suspicion of murder and is currently in police custody for questioning.
An investigation is currently underway into the circumstances surrounding their deaths.
Any with information should contact CID at Grey Mare Lane on 0161 856 3540 or call Crimestoppers, the independent charity, on 0800 555 111.
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